Following acute exposure the following drugs, who is likely to experience enhanced mesolimbic dopamine activity?

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Following acute exposure the following drugs, who is likely to experience enhanced mesolimbic dopamine activity? Beyonce is injecting heroin Aaliyah is snorting cocaine Hayden is injecting a kappa-receptor agonist Shanice is smoking methamphetamine None of the above

What is the role of the mesolimbic dopamine system in drug dependence?
Dopamine. Dopamine in the mesolimbic pathway is known to play an important role in the rewarding effects of both drugs of abuse and foods. Addictive drugs and palatable foods activate DA-containing neurons in the ventral tegmental area, which project to the nucleus accumbens (NAc).