Explore the organization of the ENS into the myenteric and submucosal plexuses

Discuss the anatomical and physiological intricacies of the enteric nervous system (ENS) and its role in gastrointestinal function and homeostasis. Explore the organization of the ENS into the myenteric and submucosal plexuses, and elucidate how it coordinates processes such as peristalsis, secretion, and blood flow regulation independently of the central nervous system. Additionally, analyze the implications of ENS dysfunction in conditions like Hirschsprung’s disease and inflammatory bowel disease, and evaluate emerging therapeutic strategies targeting enteric neurotransmission.