Water contribution to hydrophobic effect. 

 With regards to entropy, how does water contribute to the hydrophobic effect?

37. Where would you find hydrophobic amino acids on globular protein? Transmembrane protein? Why?
38. What is required for molecular surfaces/interfaces to interact with one another for a sufficient amount of time (such as an antibody/antigen)?
39. Why are weak bonds important to macromolecular structure and enzyme function?
40. Peptide bond synthesis between two amino acids produces a water. If proteins are surrounded by water,
how can this reaction even proceed without violating the 2nd Law of Thermodynamics? Why don’t proteins break down instantly upon synthesis?
41. Why are O-H or O-P (weak bonds) a better source of energy than H2O (strong bonds)?
42. What is the difference between G, G0, and G0′? Which is preferred by biochemists?
43. How can a reaction with a positive G0′ (like malate → oxaloacetate) go forward in the cell?