Explore the immunological changes involving maternal-fetal tolerance

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Discuss the anatomical and physiological adaptations of the immune system during pregnancy and the postpartum period. Explore the immunological changes involving maternal-fetal tolerance, alterations in cellular and humoral immunity, and enhanced susceptibility to certain infections. Furthermore, analyze the implications of dysregulated immune responses in pregnancy complications such as preeclampsia, preterm birth, and gestational diabetes, and evaluate strategies for optimizing maternal and fetal immune health during the perinatal period.